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Prospective Motion Correction for Brain MRI Using an External Tracking System
Kambiz Nael1,2, Puneet S Pawha2, Lazar Fleysher3
1Department of Radiological Sciences, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA.
Background And Purpose:
A wide range of strategies have been developed to mitigate motion, as a major source of image quality degradation in clinical MRI. We aimed to assess the efficiency of a commercially available prospective motion correction (PMC) system in reducing motion in acquiring high-resolution 3D magnetization-prepared rapid gradient-echo (MPRAGE).
Methods:
A total of 100 patients who referred for brain MRI studies were prospectively imaged using a 3.0T scanner. 3D MPRAGE acquisition was obtained with and without application of PMC. The motion tracking system (KinetiCor Inc.) consisted of a quad camera apparatus, which tracks a specific marker on patient's head by evaluating the marker's optical pattern. The patient's head motion in 6 degrees of freedom throughout the acquisition was then incorporated into the MRI sequence, updating the image acquisition in real time based on the most recent head pose data. MPRAGE images with and without motion correction were assessed independently by two board-certified neuroradiologists using a 5-point Likert scale. Statistical analysis included kappa and Wilcoxon Rank-Sum tests.
Results:
Observers 1 and 2 identified nondiagnostic studies in 17.2% and 20.7% of patients (K = .78, 95% CI .70-.86) without motion correction and in 5.7% and 8% of the studies with motion correction (K = .84, 95% CI .76-.92). The number of nondiagnostic studies was significantly (P = .001) reduced from 19.5% to 5.7% after motion correction in consensus read analysis.
Conclusion:
The described motion tracking system can be used effectively in clinical practice reducing motion artifact and improving image quality of 3D MPRAGE sequence.
Insights
Prospective motion correction (PMC) significantly reduces motion artifacts in brain MRI scans. This system improves image quality for high-resolution 3D MPRAGE sequences, making studies more diagnostic.
Area of Science:
- Radiology
- Medical Imaging
- Neuroimaging
Background:
- Motion is a significant factor degrading clinical MRI image quality.
- Prospective motion correction (PMC) systems offer a potential solution to mitigate motion artifacts.
- High-resolution 3D magnetization-prepared rapid gradient-echo (MPRAGE) sequences are particularly sensitive to motion.
Purpose of the Study:
- To evaluate the effectiveness of a commercial prospective motion correction (PMC) system.
- To assess the impact of PMC on reducing motion during high-resolution 3D MPRAGE acquisition.
- To determine if PMC improves diagnostic quality in brain MRI.
Main Methods:
- 100 patients undergoing brain MRI on a 3.0T scanner were prospectively imaged.
- 3D MPRAGE sequences were acquired both with and without PMC.
- A camera-based system tracked head motion in real-time, adjusting MRI acquisition accordingly.
- Two neuroradiologists independently assessed image quality using a 5-point Likert scale.
Main Results:
- The rate of nondiagnostic studies decreased significantly from 19.5% without PMC to 5.7% with PMC (P = .001).
- Inter-rater reliability for assessing diagnostic quality was high (Kappa = 0.78-0.84).
- Specific nondiagnostic rates were 17.2-20.7% without correction and 5.7-8% with correction.
Conclusions:
- The evaluated motion tracking system effectively reduces motion artifacts in clinical practice.
- Prospective motion correction significantly improves the image quality of 3D MPRAGE brain MRI.
- This technology enhances the diagnostic utility of high-resolution MRI sequences.
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