Related Experiment Videos
Mitral valve disease in Marfan's syndrome
N Marlow1, J E Gregg, S A Qureshi
1Department of Child Health, University of Liverpool.
Archives of Disease in Childhood
|September 1, 1987
Summary
Children with Marfan syndrome (MFS) often develop mitral valve disease. Early cardiovascular evaluation is crucial for suspected pediatric MFS cases to detect potential heart issues.
Area of Science:
- Cardiology
- Genetics
- Pediatrics
Background:
- Marfan syndrome (MFS) is a genetic disorder affecting connective tissue.
- Cardiovascular complications are a major cause of morbidity and mortality in MFS.
Observation:
- In pediatric cases of Marfan syndrome, cardiovascular manifestations differ from adult presentations.
- The mitral valve is more frequently affected in childhood MFS compared to the aorta or aortic valve.
Findings:
- Childhood Marfan syndrome predominantly impacts the mitral valve.
- Aortic valve and aortic root involvement, common in adults, are less prevalent in affected children.
Implications:
- Early cardiovascular assessment is vital for children with suspected Marfan syndrome.
- Prompt diagnosis and monitoring can guide timely interventions for pediatric cardiovascular complications in MFS.