Related Experiment Video
Updated: Dec 2, 2025

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Asymptomatic disseminated telangiectasias: a rare case of cutaneous collagenous vasculopathy
Yolanka Lobo1, Tristan Blake, Asoka Herat
1Department of Dermatology, Mater Hospital Brisbane, Queensland. yolanka_lobo@yahoo.com.
Abstract:
Cutaneous collagenous vasculopathy (CCV) is a rare idiopathic microangiopathy affecting superficial dermal blood vessels. It is characterized by asymptomatic, disseminated, telangiectatic macules that typically involve the extremities. We report the case of a 58-year-old woman who presented with widespread telangiectasias of three years' duration on the upper extremities and abdomen. Cutaneous collagenous vasculopathy may be underdiagnosed as it is often mistaken for disorders that are morphologically very similar, including generalized essential telangiectasia, hereditary hemorrhagic telangiectasia, and pigmented purpuric dermatosis. The diagnosis of CCV is made histologically and findings feature dilated superficial dermal vessels with thickened walls containing periodic acid-Schiff-positive eosinophilic hyaline material. Effective treatment options for CCV have yet to be established and given its benign disease course, treatment may not be necessary. Pulsed dye laser can be offered to patients for cosmetic improvement but the extent of the disease makes complete lesion clearance challenging in most cases. Given the lesions were asymptomatic our patient declined all offered treatment modalities.
Related Concept Videos
Endocarditis II: Clinical Features of Infective Endocarditis
Fibril-associated Collagen
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Type IV Collagen of Basal Lamina
A type IV collagen molecule has six alpha chains which can...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

