Staphylococcus schleiferi diabetic foot osteomyelitis and bacteraemia in an immunocompromised host

Minh Thu Thi Nguyen1, Nicholas R Ahern2, Meghan K Train2

  • 1Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA MinhThu_Nguyen@URMC.Rochester.edu.

BMJ Case Reports
|November 5, 2020
PubMed

Insights

Staphylococcus schleiferi, a bacterium rarely causing human infections, can lead to severe conditions like diabetic foot osteomyelitis and bloodstream infections in immunocompromised individuals. This case highlights the need for better diagnostic recognition of this emerging pathogen.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Clinical Bacteriology

Background:

  • Staphylococcus schleiferi is a Gram-positive coccus primarily known for causing infections in animals.
  • Its role as a human pathogen is increasingly recognized, particularly in vulnerable populations.
  • Underdiagnosis may occur due to limitations in standard microbiological identification methods.

Observation:

  • A rare case of Staphylococcus schleiferi infection is presented.
  • The infection manifested as diabetic foot osteomyelitis.
  • The patient experienced subsequent bacteraemia (bloodstream infection).

Findings:

  • The study details a specific instance of S. schleiferi causing severe invasive disease.
  • The patient was immunocompromised, a key risk factor for opportunistic infections.
  • This case underscores the potential for S. schleiferi to cause serious human infections.

Implications:

  • Highlights the importance of considering S. schleiferi in human infections, especially in immunocompromised hosts.
  • Suggests a need for improved diagnostic strategies to accurately identify S. schleiferi.
  • Contributes to understanding the evolving spectrum of Staphylococcus-related human diseases.

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