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Left Ventricular Hypertrophy Is More Prevalent in Type B than Type A Aortic Dissection

Koichi Akutsu1, Kensuke Ozaki2, Susumu Oshima2

  • 1Division of Vascular Medicine, Department of Aortic Surgery, Kawasaki Aortic Center, Kawasaki Saiwai Hospital, Kawasaki, Kanagawa, Japan.

Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
|November 5, 2020
PubMed

Insights

Left ventricular hypertrophy (LVH) is more common in type B aortic dissection (AD) than type A AD. This suggests type B patients may experience higher rates of hypertension, a common cause of LVH.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Cardiovascular Imaging

Background:

  • Aortic dissection (AD) is a serious cardiovascular condition with distinct types A and B.
  • Left ventricular hypertrophy (LVH), often linked to hypertension, has not been extensively studied in relation to AD subtypes.
  • Understanding differences in LVH prevalence between AD types can offer insights into underlying pathophysiology and patient risk stratification.

Purpose of the Study:

  • To investigate and compare the prevalence of left ventricular hypertrophy (LVH) in patients diagnosed with type A versus type B aortic dissection (AD).

Main Methods:

  • A retrospective analysis was conducted on 334 patients with acute AD (227 type A, 107 type B).
  • Left ventricular mass index (LVMI) and the prevalence of concentric hypertrophy (CH) were compared between type A and type B AD cohorts.
  • Multivariate logistic regression was employed to identify factors associated with type B AD.

Main Results:

  • Patients with type B AD exhibited significantly higher LVMI (107 ± 28 vs. 95 ± 26, p < 0.001) and a greater prevalence of CH (44% vs. 26%, p = 0.001) compared to type A AD.
  • Concentric hypertrophy (CH) was identified as an independent factor associated with type B AD (OR: 2.62, 95% CI: 1.54-4.47, p < 0.001).

Conclusions:

  • Left ventricular hypertrophy (LVH) is more prevalent in patients with type B aortic dissection (AD) than in those with type A AD.
  • The increased prevalence of LVH in type B AD suggests a potentially stronger association with hypertension in this patient group.
Abstract

Keywords:
aortic dissectionhypertensionleft ventricular hypertrophytype Atype B

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