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Left Ventricular Hypertrophy Is More Prevalent in Type B than Type A Aortic Dissection
Koichi Akutsu1, Kensuke Ozaki2, Susumu Oshima2
1Division of Vascular Medicine, Department of Aortic Surgery, Kawasaki Aortic Center, Kawasaki Saiwai Hospital, Kawasaki, Kanagawa, Japan.
Summary
Left ventricular hypertrophy (LVH) is more common in type B aortic dissection (AD) than type A AD. This suggests type B patients may experience higher rates of hypertension, a common cause of LVH.
Area of Science:
- Cardiology
- Vascular Medicine
- Cardiovascular Imaging
Background:
- Aortic dissection (AD) is a serious cardiovascular condition with distinct types A and B.
- Left ventricular hypertrophy (LVH), often linked to hypertension, has not been extensively studied in relation to AD subtypes.
- Understanding differences in LVH prevalence between AD types can offer insights into underlying pathophysiology and patient risk stratification.
Purpose of the Study:
- To investigate and compare the prevalence of left ventricular hypertrophy (LVH) in patients diagnosed with type A versus type B aortic dissection (AD).
Main Methods:
- A retrospective analysis was conducted on 334 patients with acute AD (227 type A, 107 type B).
- Left ventricular mass index (LVMI) and the prevalence of concentric hypertrophy (CH) were compared between type A and type B AD cohorts.
- Multivariate logistic regression was employed to identify factors associated with type B AD.
Main Results:
- Patients with type B AD exhibited significantly higher LVMI (107 ± 28 vs. 95 ± 26, p < 0.001) and a greater prevalence of CH (44% vs. 26%, p = 0.001) compared to type A AD.
- Concentric hypertrophy (CH) was identified as an independent factor associated with type B AD (OR: 2.62, 95% CI: 1.54-4.47, p < 0.001).
Conclusions:
- Left ventricular hypertrophy (LVH) is more prevalent in patients with type B aortic dissection (AD) than in those with type A AD.
- The increased prevalence of LVH in type B AD suggests a potentially stronger association with hypertension in this patient group.
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