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Updated: Dec 2, 2025
Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
Published on: January 15, 2013
Dynamic time domain near-infrared optical tomography based on a SPAD camera
Jingjing Jiang1, Aldo Di Costanzo Mata1, Scott Lindner1,2,3
1Biomedical Optics Research Laboratory, University Hospital Zurich and University of Zurich, Switzerland.
Abstract:
In many clinical applications it is relevant to observe dynamic changes in oxygenation. Therefore the ability of dynamic imaging with time domain (TD) near-infrared optical tomography (NIROT) will be important. But fast imaging is a challenge. The data acquisition of our handheld TD NIROT system based on single photon avalanche diode (SPAD) camera and 11 light sources was consequently accelerated. We tested the system on a diffusive medium simulating tissue with a moving object embedded. With 3D image reconstruction, the moving object was correctly located using only 0.2 s exposure time per source.
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