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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
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Microsurgical versus endoscopic surgery for non-functioning pituitary adenomas: a retrospective study
Tomáš Česák1, Pavel Póczoš, Jaroslav Adamkov
1Tomáš Česák, Department of Neurosurgery, University Hospital Hradec Kralove, Sokolská 581, 500 05 Hradec Králové, Czech Republic, tomas.cesak@fnhk.cz.
Croatian Medical Journal
|November 5, 2020
Summary
Microsurgical technique (mTSS) and endoscopic technique (eTSS) for non-functioning pituitary adenomas (NFPAs) showed similar radicality and safety. Endoscopic technique may offer better preservation of hormonal function post-surgery.
Area of Science:
- Neurosurgery
- Endocrinology
- Oncology
Background:
- Non-functioning pituitary adenomas (NFPAs) require effective surgical treatment.
- Microsurgical (mTSS) and endoscopic (eTSS) techniques are used for NFPA resection.
- Comparing these techniques is crucial for optimizing patient outcomes.
Purpose of the Study:
- To compare the efficacy and safety of microsurgical technique (mTSS) versus endoscopic technique (eTSS) in treating NFPAs.
- To evaluate differences in surgical outcomes, including resection extent, complications, and functional preservation.
Main Methods:
- Retrospective analysis of 50 patients with NFPAs treated between 2013-2019.
- Comparison of mTSS and eTSS groups based on surgery duration, blood loss, resection extent, and complication rates.
- Assessment of endocrinological, ophthalmological deficits, and tumor regrowth patterns.
Main Results:
- Microsurgical technique (mTSS) demonstrated significantly shorter surgical times and lower blood loss compared to eTSS.
- No significant differences were observed in the extent of resection, clinical effect, hormonal outcomes, or complication rates between the two techniques.
- Tumor consistency did not correlate with resection extent, nor did tumor growth rate correlate with age or Ki-67 expression.
Conclusions:
- Both mTSS and eTSS are comparable in terms of surgical radicality and safety for NFPA treatment.
- Endoscopic technique (eTSS) is suggested as the preferred method due to potentially superior postoperative preservation of hormonal functions.
