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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

120
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
120
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

106
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
106
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

154
In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
154
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

116
As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
116
Aging01:26

Aging

462
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
462
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

102
Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
102

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Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
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Geriatric Engineering: An Engineering Systems Design Approach to Human Aging.

David J Lubliner1

  • 1Medical Informatics Technology / School of Applied Engineering and Technology, New Jersey Institute of Technology, Newark, New Jersey, USA.

Journal of the American Geriatrics Society
|November 5, 2020
PubMed
Summary

Developing a Geriatric Engineering Bachelor of Science degree program addresses the growing need for engineers skilled in designing cost-effective solutions for an aging population. Positive student feedback and data from older adults support this specialized undergraduate program.

Keywords:
deep learninggeriatricspredictive analyticsproactive medicinesystem engineering

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Area of Science:

  • Geriatric Engineering
  • Interdisciplinary Studies
  • Biomedical Engineering Education

Background:

  • The economics of aging necessitates engineers trained in designing systems to reduce healthcare costs.
  • A significant portion of individuals over 60 desire technological assistance for independent living.
  • Existing graduate programs demonstrate precedents for medical-engineering curricula.

Purpose of the Study:

  • To explore the development of an interdisciplinary Geriatric Engineering Bachelor of Science degree program.
  • To assess the need and gather supporting data for a dedicated undergraduate program.
  • To outline the 5-year process from initial exploration to curriculum development.

Main Methods:

  • Conducted literature searches to identify needs and precedents.
  • Acquired data from individuals aged 60-92 via questionnaires and interviews.
  • Introduced and evaluated geriatric engineering courses, gathering student feedback.
  • Established an Advisory Board comprising medical professionals, industry representatives, and target population members.

Main Results:

  • Literature confirmed the need for medical and engineering collaboration.
  • Data indicated strong desire among older adults for technology to support independent living.
  • Geriatric engineering courses introduced in 2017 received positive student feedback (>100 students).
  • A Geriatric Engineering minor was established in 2019, supported by an Advisory Board.

Conclusions:

  • Student feedback, data from older adults, and advisory board input support the creation of a Geriatric Engineering Bachelor's degree.
  • Positive student evaluations of courses indicate program viability.
  • Evidence suggests a clear need for a dedicated undergraduate Geriatric Engineering program to meet the demands of an aging population.