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Epitope masking may limit antibody boosting to malaria vaccines
Liriye Kurtovic1,2, Michelle J Boyle1,3, James G Beeson1,2,4,5
1Burnet Institute, Melbourne, VIC, Australia.
Immunology and Cell Biology
|November 5, 2020
Abstract:
We discuss the study by McNamara et al., who report that low levels of antigen-specific antibodies in serum can limit the boosting of antibody and B-cell responses following immunization with live attenuated malaria sporozoites.
