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Updated: Dec 2, 2025
Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
Bilateral acute retinal necrosis with encephalitis in a premature infant
Kevin Mairot1, Prithvi Ramtohul1, Pierre Gascon1
1Department of Ophthalmology, Centre Hospitalier Universitaire de l'Hôpital Nord, Marseille, France.
Introduction:
Neonatal herpes infections can be extremely severe and their early recognition allows for appropriate management and increases the child's chances of survival.
Case Description:
We report the case of a premature infant born by vaginal delivery and transferred to intensive care after neonatal misadaptation. Examination of the fundus revealed lesions of acute bilateral retinal necrosis, strongly suggesting a herpetic etiology.
Conclusions:
This case highlights the clinical benefit of an ophthalmologic exam in newborns with equivocal brain lesions. Herein, the fundus examination allowed for high suspicion of herpes virus infection.
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