Complete Genome Sequence of Serratia marcescens FY, Isolated from Drosophila melanogaster

Wei Liu1,2, Ruxue Kang2, Kah Leong Lim3,4

  • 1Department of Neurology, National Neuroscience Institute, Singapore, Singapore liuwei@sxmu.edu.cn tan.eng.king@singhealth.com.sg.

Insights

We sequenced the genome of Serratia marcescens strain FY, isolated from fruit flies. This provides a valuable resource for understanding insect-pathogen interactions and host defense mechanisms.

Area of Science:

  • Microbiology
  • Genomics
  • Insect Pathology

Background:

  • Fruit flies (Drosophila) are susceptible to various pathogens, impacting host fitness.
  • Serratia marcescens is a known opportunistic pathogen that can infect insects.

Purpose of the Study:

  • To present the complete genome sequence of Serratia marcescens strain FY.
  • To provide a genomic resource for studying fruit fly-Serratia marcescens interactions.

Main Methods:

  • Isolation of Serratia marcescens strain FY from a Drosophila specimen's intestines.
  • Whole-genome sequencing and assembly of the bacterial strain.
  • Bioinformatic analysis to predict coding sequences.

Main Results:

  • The complete genome sequence of Serratia marcescens strain FY was determined.
  • The genome consists of a chromosome (5,074,453 bp) and two plasmids (100,934 bp and 87,789 bp).
  • A total of 4,891 coding sequences were predicted.

Conclusions:

  • The genome sequence of Serratia marcescens strain FY is now available.
  • This genomic data will facilitate research into Drosophila immunity and bacterial pathogenesis.

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