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Practical early cancer detection: distinguishing stable from unstable genomes in pre-cancerous tissues
Sarah Killcoyne1,2, Rebecca C Fitzgerald3
1Medical Research Council Cancer Unit, Hutchison/Medical Research Council Research Centre, University of Cambridge, Cambridge, UK.
British Journal of Cancer
|November 6, 2020
Abstract:
Barrett's oesophagus has been known for many years to display early changes to the genome consistent with the risk for oesophageal adenocarcinoma. Recently we have shown that this information can be used without knowledge of individual gene mutations to accurately predict a patient's future risk of malignant progression.
