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Effect of miR-26a on diabetic rats with myocardial injury by targeting PTEN
1Department of Cardiovascular Medicine, Department of Neonatal Medicine; Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Abstract:
Since this article has been suspected of research misconduct and the corresponding authors did not respond to our request to prove originality of data and figures, "Effect of miR-26a on diabetic rats with myocardial injury by targeting PTEN, by S.-S. Cai, X.-W. Tao, Y. Long, K. Xia, Y. Zhang, published in Eur Rev Med Pharmacol Sci 2019; 23 (3 Suppl): 304-311-DOI: 10.26355/eurrev_201908_18661-PMID: 31389595" has been withdrawn. The Publisher apologizes for any inconvenience this may cause. https://www.europeanreview.org/article/18661.
Insights
This study on miR-26a and diabetic myocardial injury in rats has been withdrawn due to suspected research misconduct. The publisher retracted the article as authors failed to prove data originality.
Area of Science:
- Biomedical Science
- Cardiovascular Research
- Diabetology
Background:
- Diabetic cardiomyopathy is a significant complication of diabetes mellitus.
- MicroRNAs (miRNAs) play a crucial role in regulating cardiac function.
- PTEN is implicated in cardiac hypertrophy and fibrosis.
Purpose of the Study:
- To investigate the effect of miR-26a on myocardial injury in diabetic rats.
- To explore the potential mechanism involving PTEN.
Main Methods:
- Animal model of diabetic myocardial injury in rats.
- Assessment of cardiac function and histopathology.
- Molecular analysis of miR-26a and PTEN expression.
Main Results:
- The study aimed to demonstrate miR-26a's protective effect against diabetic myocardial injury.
- It proposed that miR-26a targets PTEN, influencing cardiac pathology.
Conclusions:
- The article has been withdrawn due to suspected research misconduct.
- Authors failed to provide evidence for data and figure originality upon request.
