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Immunotherapeutic strategies in breast cancer: A clinical update

Jennifer Q Zhang1, George Plitas1,2

  • 1Department of Surgery, Breast Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

Journal of Surgical Oncology
|November 6, 2020
PubMed

Immunotherapy has been incorporated into the standard of care for a wide range of malignancies. The study of tumor-infiltrating lymphocytes has emphasized the importance of the host antitumor immune response in the natural history of breast cancer. Recent clinical trials have used immunotherapeutic approaches to augment this response and improve outcomes for patients with breast cancer. Here, we review several current clinical trial data that indicate checkpoint blockade may mediate clinically significant responses.

Keywords:
checkpoint blockadeimmunotherapyoutcomes

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