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Updated: Dec 1, 2025

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Elderly patients, isometric exercise, and native vascular access maturation: An unsolved question?
Irati Tapia González1,2,3, Vicent Esteve Simó1,2, Sara Ibañez1,4
1Funtional Unit Vascular Access (FUVA), Nephrology Department, Consorci Sanitari Terrassa (CST), Barcelona, Spain.
Postoperative isometric exercises improved vascular access maturation in elderly hemodialysis patients. This intervention enhanced fistula function and reduced complications, suggesting its value for older adults.
Area of Science:
- Nephrology
- Vascular Surgery
- Geriatrics
Background:
- Increasing number of elderly patients require hemodialysis.
- Vascular access (VA) selection and management in this population present unique challenges.
- The impact of postoperative isometric exercises on native VA maturation in the elderly is not well-established.
Purpose of the Study:
- To evaluate the effect of postoperative isometric exercises on native VA maturation in patients over 75 years old with advanced chronic kidney disease.
Main Methods:
- A 24-month, single-center randomized study.
- Exercise group (EG) performed isometric exercises; control group (CG) received usual care.
- Assessed handgrip strength, Doppler ultrasound (DUS), VA complications, and maturation at 4 and 8 weeks.
Main Results:
- 27 elderly patients (mean age 79.9 years) were included.
- The EG showed significant increases in handgrip strength and higher rates of clinical (78.6% vs. 46.2%) and DUS maturation (71.4% vs. 30.8%) at 8 weeks.
- Lower incidence of VA stenosis was observed in the EG (7.1% vs. 23.1%).
Conclusions:
- Postoperative isometric exercises should be considered for elderly patients undergoing native VA creation.
- This intervention may improve the likelihood of achieving a mature, functional arteriovenous fistula.
- Further research is needed to validate these findings in the elderly population.
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