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Nanodiamonds for bioapplications, recent developments.

Nicolas Bondon1, Laurence Raehm, Clarence Charnay

  • 1Institut Charles Gerhardt Montpellier, UMR 5253, CNRS-UM-ENSCM, Université de Montpellier, Place Eugène Bataillon 34095, Montpellier cedex 05, France. nicolas.bondon@umontpellier.fr.

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Nanodiamonds (NDs) show promise in biomedicine due to their unique properties. This review highlights recent advances in ND applications for anticancer, antimicrobial, and bioimaging uses, alongside therapeutic and diagnostic combinations.

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Area of Science:

  • Biomedical research
  • Materials science
  • Nanotechnology

Background:

  • Biomedical research requires stringent pre-clinical and clinical study conditions.
  • Nanodiamonds (NDs) possess unique optical, thermal, and mechanical properties, leading to increased interest in bioapplications.
  • Understanding NDs' in vitro and in vivo efficiency and compatibility is crucial.

Purpose of the Study:

  • To review the latest advancements in nanodiamond applications within the biomedical field.
  • To provide an overview of the potential features of nanodiamonds for therapeutic and diagnostic purposes.
  • To consolidate key information from recent nanodiamond research.

Main Methods:

  • Literature review of recent scientific works on nanodiamonds in bioapplications.
  • Analysis of nanodiamond synthesis, modification, purification, and characterization.
  • Evaluation of nanodiamonds' performance in various biomedical contexts.

Main Results:

  • Nanodiamonds are explored for anticancer and antimicrobial systems.
  • Applications in wound healing and tissue engineering are discussed.
  • Nanodiamonds show potential as bioimaging and labeling probes, with emerging therapeutic and diagnostic combinations.

Conclusions:

  • Nanodiamonds offer versatile properties for diverse biomedical applications.
  • Further research into nanodiamonds' characteristics can optimize their use in medicine.
  • Nanodiamonds are a promising platform for integrated therapeutic and diagnostic strategies.