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Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

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Published on: July 5, 2021

Diffuse pulmonary meningotheliomatosis.

Gabin Yun¹, Tao Huang², David O'Dwyer³

¹Department of Radiology, Division of Cardiothoracic Radiology, University of Pittsburgh Medical Center, Pittsburgh, USA.

Clinical Imaging

|November 6, 2020

Summary

This summary is machine-generated.

An 80-year-old woman with diffuse pulmonary meningotheliomatosis (DPM) showed random lung nodules. Diagnosis involved imaging, clinical context, and surgical biopsy, highlighting an organized approach to this rare condition.

Keywords:

Benign CT Diffuse pulmonary meningotheliomatosis Imaging Lung nodules Pulmonary

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Area of Science:

Pulmonology
Pathology
Radiology

Background:

Diffuse pulmonary meningotheliomatosis (DPM) is a rare condition characterized by the proliferation of meningothelial-like cells in the lungs.
Its imaging findings can be nonspecific, often mimicking other interstitial lung diseases.
An organized diagnostic approach is crucial for accurate identification.

Observation:

An 80-year-old female presented with randomly distributed ground-glass nodules on lung imaging.
The nodules were persistent over time and considered in conjunction with the patient's clinical presentation.
This pattern prompted further investigation beyond common lung pathologies.

Findings:

The characteristic imaging appearance, prolonged nodule presence, and clinical context suggested DPM.
Surgical lung biopsy was essential for definitive diagnosis, confirming the presence of meningothelial-like cells.
Review of literature supports an algorithmic approach for diagnosing DPM.

Implications:

This case underscores the importance of considering rare diagnoses like DPM in patients with unusual lung imaging findings.
An integrated approach combining imaging, clinical data, and histopathology aids in diagnosing DPM.
Further research into DPM imaging characteristics and diagnostic pathways is warranted.