Caudal Regression Syndrome
Ranjit I Kylat1, Mohammad Bader1
1Department of Pediatrics, University of Arizona, College of Medicine, Tucson, AZ 85724, USA.
Children (Basel, Switzerland)
|November 7, 2020
Summary
Caudal Regression Syndrome (CRS) is a rare birth defect affecting the lower body. Early diagnosis and a multidisciplinary approach are crucial for managing this complex condition.
Area of Science:
- Pediatric congenital anomalies
- Developmental biology
- Genetics of birth defects
Background:
- Caudal Regression Syndrome (CRS), also known as Caudal dysgenesis syndrome (CDS), involves maldevelopment of the body's caudal half.
- It affects multiple systems including gastrointestinal, genitourinary, skeletal, and nervous systems.
- CRS incidence is 1-3 per 100,000 live births, significantly higher (1 in 350) in infants of diabetic mothers.
