[Immuno-oncologic aspects in invasive squamous cell carcinoma of the uterine cervix]

Five patients with an invasive squamous cell carcinoma of the cervix uteri were investigated histologically and immunohistologically to assess localization and composition of the lymphoreticular infiltrates. The relevant cell populations of local immunomechanisms (T-lymphocytes, monocytes/macrophages and plasma cells) were often found numerous in all neoplasms. It must be emphasized that an in situ histomorphological analysis of the cellular part of the stromal reaction of invasive squamous cell carcinoma of the cervix allows only limited conclusions concerning the functional properties of the tumor-infiltrating lymphoreticular cells.