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Fluorescence-based Neuraminidase Inhibition Assay to Assess the Susceptibility of Influenza Viruses to The Neuraminidase Inhibitor Class of Antivirals
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Two mAbs take a stab at influenza's NActive site

Minh C Pham1, Kevin C O'Connor1

  • 1Departments of Neurology and Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA. Email: minh.pham@yale.edu; kevin.oconnor@yale.edu.

Science Immunology
|November 7, 2020
PubMed

Two human-derived recombinant mAbs specific for IBV bind the neuraminidase active site by emulating the enzymatic substrate, which results in broad protection.

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