Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Fungal Phylum Microsporidia

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...

Diversity of Protists II

Diversity of Protists II

Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...

Diversity of Protists I

Diversity of Protists I

Excavata is a diverse group of protists that includes both chemoorganotrophic and phototrophic species, with some thriving in anaerobic environments. Among the key groups within Excavata are diplomonads and parabasalids, which are flagellated protists that lack mitochondria and chloroplasts. These microorganisms typically inhabit anoxic environments, such as the intestines of animals, where they exist either symbiotically or as parasites, relying on fermentation for energy production. Some...

Symbiosis

Symbiosis

Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Norditerpene Natural Products from Subterranean Fungi with Anti-Parasitic Activity.

Microorganisms·2025

Same author

Targeting the interaction between long noncoding RNA XR_001779380 and Prdm1 to enhance IFN-γ immunity in murine neonatal intestinal epithelial cells.

mBio·2025

Same author

Tartrolon E rapidly blocks Toxoplasma gondii capacity to invade host cells.

International journal for parasitology. Drugs and drug resistance·2025

Same author

A new method to replace oral gavage for the study of <i>Cryptosporidium</i> infection in mice.

Laboratory animals·2025

Same author

Norditerpene natural products from subterranean fungi with anti-parasitic activity.

bioRxiv : the preprint server for biology·2025

Same author

Tartrolon E, a secondary metabolite of a marine symbiotic bacterium, is a potent inhibitor of asexual and sexual <i>Plasmodium falciparum</i>.

Antimicrobial agents and chemotherapy·2024

Search research articles

Related Experiment Video

Updated: Dec 1, 2025

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection

Published on: September 14, 2019

Cryptosporidium: host and parasite transcriptome in infection.

Rachel M Bone Relat¹, Roberta M O'Connor¹

¹Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, WA, USA.

Current Opinion in Microbiology

|November 7, 2020

Summary

Cryptosporidium, a waterborne parasite causing global diarrheal disease, lacks effective treatments. New transcriptomic approaches analyzing its life cycle promise to uncover therapeutic targets.

More Related Videos

High-Throughput Transcriptome Analysis for Investigating Host-Pathogen Interactions

High-Throughput Transcriptome Analysis for Investigating Host-Pathogen Interactions

Published on: March 5, 2022

Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases

Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases

Published on: November 22, 2024

Related Experiment Videos

Last Updated: Dec 1, 2025

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection

Published on: September 14, 2019

High-Throughput Transcriptome Analysis for Investigating Host-Pathogen Interactions

High-Throughput Transcriptome Analysis for Investigating Host-Pathogen Interactions

Published on: March 5, 2022

Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases

Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases

Published on: November 22, 2024

Area of Science:

Parasitology
Molecular Biology
Infectious Diseases

Background:

Cryptosporidium is a significant waterborne protozoan parasite responsible for worldwide diarrheal disease outbreaks.
Current therapeutic and vaccine options for Cryptosporidium infections are limited, highlighting an urgent need for novel interventions.
Understanding host-parasite interactions is crucial for identifying potential drug and vaccine targets.

Purpose of the Study:

To explore the utility of transcriptomic data in understanding Cryptosporidium host-parasite interactions.
To address the challenges in interpreting Cryptosporidium transcriptomes.
To highlight how recent advancements can improve transcriptomic analysis for therapeutic target identification.

Main Methods:

Review and synthesis of current challenges in Cryptosporidium research.
Discussion of the potential of transcriptomic analysis.
Highlighting recent technological improvements in parasite culturing and life stage isolation.

Main Results:

Interpreting Cryptosporidium transcriptomes is complex due to multiple life stages and culturing difficulties.
Recent advancements in cell culture and stage-specific isolation are improving data quality.
These improvements are expected to enhance the understanding of host-parasite interactions.

Conclusions:

Improved transcriptomic data analysis holds significant promise for advancing Cryptosporidium research.
New insights gained will be vital for developing effective drugs and vaccines against this important pathogen.
Technological advancements are key to overcoming previous limitations in studying Cryptosporidium.