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Single dose of intraoperative intravenous morphine for analgesia in children undergoing tonsillectomy: Randomized,

Marcus Cavalcante de Oliveira Araújo1, Juliana Alves de Sousa Caixeta2, Breno Fernandes Vilarinho1

  • 1Universidade Federal de Goiás, Goiânia, GO, Brazil.

Brazilian Journal of Otorhinolaryngology
|November 9, 2020
PubMed

Insights

Intraoperative intravenous morphine effectively reduced immediate postoperative pain in children undergoing tonsillectomy. This approach also led to lower analgesic use without increasing anesthesia recovery time.

Area of Science:

  • Pediatric Anesthesiology
  • Pain Management
  • Surgical Recovery

Background:

  • Post-tonsillectomy pain is severe in children.
  • Opioids like morphine are effective analgesics but carry risks.
  • Morphine's adverse effects can limit its use in pediatric patients.

Purpose of the Study:

  • To evaluate the efficacy of intraoperative intravenous morphine for immediate postoperative pain relief in children undergoing tonsillectomy.
  • To assess the impact of morphine on anesthesia recovery time and analgesic consumption.

Main Methods:

  • Double-blind, randomized study involving 57 children aged 3-10 years undergoing tonsillectomy.
  • Group M received 0.1 mg/kg intravenous morphine during induction; control group received standard anesthesia.
  • Postoperative pain assessed using a facial pain scale by children and parents at multiple time points.

Main Results:

  • Children receiving morphine reported less pain at 30 minutes post-awakening.
  • Parents/guardians reported significantly less pain in the morphine group at 30, 60, and 180 minutes.
  • Morphine group required fewer postoperative analgesics, with no observed side effects.

Conclusions:

  • A single intraoperative dose of intravenous morphine effectively reduces immediate postoperative pain intensity in pediatric tonsillectomy patients.
  • Morphine administration did not prolong anesthesia emergence time.
  • Intravenous morphine is a safe and effective option for managing pain after tonsillectomy in children.
Abstract

Keywords:
AnalgesiaAnesthesiaChildMorphineTonsillectomy

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