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Malignant melanoma arising in an ovarian cystic teratoma in pregnancy
R S Boughton1, S Hughmanick, M Marin-Padilla
1Department of Pathology, Dartmouth-Hitchcock Medical Center, Hanover, NH 03756.
Ovarian cystic teratoma is a common neoplasm, but malignant melanoma arising within such a tumor is exceedingly rare. The small number of previous cases generally occurred in older individuals, usually with a poor outcome. The patient presented herein is remarkable for her youth and an optimistic prognosis. Hers is also the first such case to be associated with pregnancy. The relevant literature is briefly reviewed.
Ovarian cystic teratoma is a common neoplasm, but malignant melanoma arising within such a tumor is exceedingly rare. The small number of previous cases generally occurred in older individuals, usually with a poor outcome. The patient presented herein is remarkable for her youth and an optimistic prognosis. Hers is also the first such case to be associated with pregnancy. The relevant literature is briefly reviewed.