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Related Experiment Video

Updated: Dec 1, 2025

Inducement and Evaluation of a Murine Model of Experimental Myopia

Inducement and Evaluation of a Murine Model of Experimental Myopia

Published on: January 22, 2019

Aripiprazole-induced transient myopia.

Tongabay Cumurcu¹, Birgul Elbozan Cumurcu², Bahar Yesil²

¹Department of Ophthalmology, Inonu University Faculty of Medicine, Malatya, Turkey.

Northern Clinics of Istanbul

|November 9, 2020

Summary

This summary is machine-generated.

Transient myopia, a temporary vision change, can occur with the antidepressant aripiprazole. Discontinuing the drug resolved the myopia, highlighting the importance of patient monitoring for ocular side effects.

Keywords:

Aripiprazol myopia otorefractometer pentacam

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Area of Science:

Ophthalmology
Psychiatry
Pharmacology

Background:

Aripiprazole is an atypical antipsychotic used to treat depression.
Ocular side effects of medications can impact patient treatment and outcomes.

Observation:

A 21-year-old female experienced sudden blurred vision while on aripiprazole for depression.
Her myopia increased from -3.75 D to -6.0 D, with visual acuity reduced to 6/10.

Findings:

Discontinuation of aripipiprazole led to a complete resolution of myopia and restoration of visual acuity to 10/10 within one month.
Anterior segment measurements showed subtle changes, suggesting potential mechanisms like ciliary spasm or effusion.

Implications:

Clinicians should be aware of the potential for transient myopia as a side effect of aripipiprazole.
Informing patients about potential visual disturbances is crucial for safe and effective treatment.