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Pulsed Radiofrequency Ablation: An Alternative Treatment Modality for Radiation-Induced Brachial Plexopathy
Neal Shah1, Alyson M Engle1, Eugene Raggi1
1Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Pain Medicine (Malden, Mass.)
|November 9, 2020
Summary
Radiation-induced brachial plexopathy (RIBP) is a neurotoxic side effect of radiation therapy, often occurring after high doses (over 55 Gy). This condition affects patients treated for cancers like breast, lung, or lymphoma, causing arm numbness and pain.
Area of Science:
- Oncology
- Neurology
- Radiology
Background:
- Radiation therapy is a cornerstone in treating neoplastic diseases.
- Radiation-induced neurotoxicity is a significant adverse effect.
- Radiation-induced brachial plexopathy (RIBP) results from radiation damage to brachial plexus nerves.
Purpose of the Study:
- To summarize the understanding of radiation-induced brachial plexopathy.
- To outline the incidence, symptoms, diagnosis, and management of RIBP.
Main Methods:
- Literature review of radiation therapy side effects.
- Analysis of clinical presentations and diagnostic imaging findings.
- Summary of current treatment modalities for RIBP.
Main Results:
- RIBP incidence is 1-2% in the US, often seen in breast, lung, or lymphoma cancer survivors.
- Symptoms include arm numbness, paresthesia, dysesthesia, and mild to moderate shoulder/arm pain.
- Diagnosis relies on clinical evaluation and imaging to exclude malignancy.
Conclusions:
- RIBP is a recognized complication of radiation therapy, particularly with doses exceeding 55 Gy.
- Management strategies focus on physical therapy and pharmacologic interventions.
- Further research may elucidate more targeted treatment options.
