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Visualization of Metabolites Identified in the Spatial Metabolome of Traditional Chinese Medicine Using DESI-MSI
Published on: December 16, 2022
[Research progress on chemical constituents and pharmacological effects of Sedum sarmentosum]
Yang Ying-Ying1, Wan Xin-Huan1, Liu Ying-Nan1
1College of Pharmacy, Shandong University of Traditional Chinese Medicine Ji'nan 250355, China.
Abstract:
Sedum sarmentosum is a traditional Chinese medicine with the clinical effects of clearing away heat and detoxification. It has the pharmacological effects of protecting liver, anti-tumor, anti-fibrosis, anti-oxidation, inhibiting lipid accumulation and immunosuppression. Because of its remarkable effect of reducing enzymes and protecting the liver, it is mainly used for the treatment of various types of hepatitis in clinical application. The flavonoids, megastigmanes, alkaloids, sterols, triterpenes and other chemical constituents in S. sarmentosum are the important material basis for its pharmacological action. In this paper, the research progress on the chemical constituents and pharmacological effects of S. sarmentosum were reviewed, and the research status and research direction of S. sarmentosum were analyzed, in order to provide a reference for its further rational development and application.
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