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Published on: June 4, 2012
Rothia spp. infective endocarditis: A systematic literature review
F Franconieri1, O Join-Lambert2, C Creveuil3
1Department of Infectious and Tropical Diseases, Normandie Univ, UNICAEN, CHU de Caen Normandie, 14000 Caen, France.
Rothia infective endocarditis (RIE) is a rare condition, often linked to dental issues or intravenous drug use (IVDU). Despite its rarity, RIE shows a favorable prognosis, with effective antibiotic treatment and surgery when needed.
Area of Science:
- Infectious Diseases
- Cardiology
- Microbiology
Background:
- Rothia species are increasingly recognized as pathogens.
- Infective endocarditis (IE) and extracardiac infections (ECI) caused by Rothia are rare.
- Understanding the characteristics of these infections is crucial for diagnosis and management.
Purpose of the Study:
- To comprehensively describe the epidemiological, clinical, microbiological, and therapeutic features of Rothia infective endocarditis (RIE).
- To detail the outcomes of RIE and compare them with Rothia extracardiac infections (ECRI).
Main Methods:
- A systematic literature review was conducted.
- Published cases of RIE and ECRI were analyzed.
- A personal case report was included for analysis.
Main Results:
- 51 cases of RIE and 215 cases of ECRI were identified.
- RIE patients were more frequently male, intravenous drug users (IVDU), and immunocompetent compared to ECRI patients.
- R. dentocariosa was the predominant species in RIE cases; treatment often involved beta-lactam antibiotics and surgery.
Conclusions:
- Rothia infective endocarditis is rare, often originating from dental or inoculation sources in IVDU.
- The prognosis for RIE appears favorable.
- Further research may elucidate optimal treatment strategies.
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