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Lung cancer in China: current and prospect
Fengying Wu1, Lei Wang, Caicun Zhou
1Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Current Opinion in Oncology
|November 9, 2020
Summary
Lung cancer is a significant health challenge in China, with increasing incidence and mortality. Research highlights unique genetic profiles and recommends tailored prevention and treatment strategies for the Chinese population.
Area of Science:
- Oncology
- Public Health
- Genetics
Background:
- Lung cancer poses a major public health issue in China due to rising incidence and mortality.
- Distinct genetic profiles in Chinese lung cancer include high EGFR mutation rates, low KRAS mutation rates, and frequent HBV infection comorbidity.
Purpose of the Study:
- To provide a comprehensive overview of the current status of lung cancer in China.
- To cover key aspects including incidence, prevention, molecular testing, and treatment modalities.
Main Methods:
- Review of current literature and clinical practice guidelines.
- Analysis of epidemiological data and treatment outcomes specific to China.
Main Results:
- Targeted therapy has shown significant progress in lung cancer treatment.
- Immunotherapy development in China is rapidly advancing with numerous drugs under investigation.
- Local guidelines are recommended, considering drug accessibility and regional disparities.
Conclusions:
- Achievements in lung cancer prevention and treatment exist, but shortcomings remain.
- Further research and tailored strategies are crucial, addressing the unique characteristics of lung cancer in China.
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