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Related Experiment Videos

Urgent priority transplantation: when should it be done?

L W Stevenson1, B C Donohue, J H Tillisch

  • 1Division of Cardiology, UCLA Medical Center 90024-1679.

The Journal of Heart Transplantation
|September 1, 1987
PubMed
Summary
This summary is machine-generated.

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Intensive medical therapy can stabilize some heart transplant candidates, allowing for elective procedures. However, urgent heart transplantation still carries a higher risk of early mortality compared to regular priority transplants.

Area of Science:

  • Cardiology
  • Transplantation Medicine
  • Critical Care Medicine

Background:

  • Heart transplantation success leads to longer waiting lists.
  • Urgent transplantation decisions are critical for patient outcomes.
  • Some patients refractory to medical therapy may be candidates for stabilization.

Purpose of the Study:

  • To assess if intensive medical therapy can stabilize patients for elective heart transplantation.
  • To determine the outcomes of patients undergoing urgent heart transplantation.
  • To analyze the impact of urgent transplantation on patient survival rates.

Main Methods:

  • 40 patients transferred for urgent heart transplantation received intensive vasodilator and diuretic therapy.
  • Outcomes were determined, including discharge rates and survival.
Keywords:
Empirical ApproachProfessional Patient RelationshipUCLA Medical Center (Los Angeles)

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  • Survival data for urgent priority candidates in the western region were analyzed.

    • Main Results:

    • 80% of patients (32/40) were discharged on oral medical therapy.
    • 6-month survival on medical therapy was 75%, despite severe cardiac dysfunction (ejection fraction 0.15).
    • Urgent priority patients had a 4.5 times greater risk of early mortality (p=0.02) compared to regular priority patients.

    Conclusions:

    • Intensive medical therapy can stabilize a significant portion of heart transplant candidates.
    • Urgent heart transplantation is associated with increased early mortality risk.
    • Careful patient selection and management are crucial for optimizing outcomes in heart transplantation.