Related Experiment Video
Updated: Dec 1, 2025

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
Published on: April 14, 2016
Physical activity and cold pain tolerance in the general population
Anders P Årnes1,2, Christopher S Nielsen3,4, Audun Stubhaug4,5
1Department of Pain, Department of Community Medicine, University Hospital of North Norway, Tromsø, Norway.
Higher self-reported physical activity (PA) is linked to greater experimental pain tolerance, particularly in men. This association was not observed with accelerometer-measured PA, suggesting differences in how activity is assessed.
Area of Science:
- Pain research
- Exercise science
- Epidemiology
Background:
- Previous studies on physical activity (PA) and pain tolerance used small samples.
- The relationship between habitual PA and experimental pain tolerance requires investigation in diverse populations.
Purpose of the Study:
- To examine the association between habitual physical activity and experimental pain tolerance in a large, population-based sample.
- To investigate potential sex and chronic pain status differences in this relationship.
Main Methods:
- Utilized data from the Tromsø Study (2007-2016) with 19,087 participants.
- Assessed pain tolerance using the cold pressor test (CPT) and self-reported habitual PA.
- Employed Cox regression, analyzing interactions for PA with sex and chronic pain status.
Main Results:
- Leisure-time PA, exercise intensity, and duration were positively associated with CPT pain tolerance.
- Men exhibited significantly higher CPT tolerance than women at high PA levels.
- Accelerometer-measured PA showed no association with CPT tolerance.
Conclusions:
- Higher self-reported habitual PA is associated with increased experimental pain tolerance in a population-based sample, especially in men.
- A discrepancy exists between self-reported and accelerometer-measured PA regarding pain tolerance.
- Findings suggest physical activity may enhance pain tolerance in the general population.
Related Concept Videos
Thermosensation
Responses to Heat and Cold Stress
Decreased Body Temperature
Requirements for Human Life
Oxygen
Atmospheric air is only about 20 percent oxygen, but that oxygen is a key component of the chemical reactions that keep the body alive, including the reactions that produce ATP. Brain cells are susceptible to a lack of oxygen because they require a...
Factors Affecting Body Temperature
Factors may include:
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

