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A BH Borenium-Derived Thioxoborane, Its Persulfide, and Their Li+-Induced Reactions with Alkynes and with Carbon

Chaohuang Chen1, Constantin G Daniliuc1, Christian Mück-Lichtenfeld1

  • 1Organisch-Chemisches Institut, Westfälische Wilhelms-Universität Münster, Corrensstraße 40, 48149 Münster, Germany.

Journal of the American Chemical Society
|November 9, 2020
PubMed

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One of the convenient methods for the preparation of aldehydes and ketones is via hydration of alkynes. Hydroboration-oxidation of alkynes is an indirect hydration reaction in which an alkyne is treated with borane followed by oxidation with alkaline peroxide to form an enol that rapidly converts into an aldehyde or a ketone. Terminal alkynes form aldehydes, whereas internal alkynes give ketones as the final product.
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