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The international nucleotide sequence database collaboration.

Masanori Arita1, Ilene Karsch-Mizrachi2, Guy Cochrane3

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|November 9, 2020
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Summary
This summary is machine-generated.

The International Nucleotide Sequence Database Collaboration (INSDC) provides essential nucleotide sequence data and metadata. This global effort, maintained by DDBJ, ENA, and GenBank, benefits science and the worldwide community.

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Area of Science:

  • Bioinformatics
  • Genomics
  • Molecular Biology

Background:

  • The International Nucleotide Sequence Database Collaboration (INSDC) has served as a foundational infrastructure for over 30 years.
  • It facilitates the collection and dissemination of critical nucleotide sequence data and associated metadata.

Purpose of the Study:

  • To highlight the longstanding role and collaborative nature of the INSDC.
  • To emphasize the INSDC's contribution to the scientific community and the broader public.

Main Methods:

  • The INSDC is maintained through a collaborative effort involving three major international organizations.
  • These organizations include the DNA Data Bank of Japan (DDBJ), the European Nucleotide Archive (ENA), and GenBank at NCBI.

Main Results:

  • The INSDC has successfully provided a stable and accessible platform for nucleotide sequence data for more than three decades.
  • The collaborative maintenance ensures the integrity and availability of a vast repository of genetic information.

Conclusions:

  • The INSDC represents a vital, enduring resource for biological research and data sharing.
  • Its continued collaborative operation underscores its importance to global scientific advancement and community access to genetic data.