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Toward low-voltage dielectrophoresis-based microfluidic systems: A review
Cinthia J Ramirez-Murillo1, J Martin de Los Santos-Ramirez1, Victor H Perez-Gonzalez1
1Tecnologico de Monterrey, School of Engineering and Sciences, Monterrey, México.
Electrophoresis
|November 9, 2020
Summary
Dielectrophoresis (DEP) microfluidics are vital for point-of-care diagnostics. This review highlights advances in reducing the input voltage needed for DEP, enhancing device portability and practicality.
Area of Science:
- Biomedical Engineering
- Diagnostic Medicine
- Biological Research
Background:
- Dielectrophoretically driven microfluidic devices offer significant potential in various scientific fields.
- Point-of-care (POC) devices aim for portable, integrated, user-friendly, and low-cost diagnostic platforms.
- Two primary methods for inducing dielectrophoresis (DEP) are electrode-based and insulator-based DEP, each with unique pros and cons.
Purpose of the Study:
- To review recent advancements in reducing the stimulation voltage requirements for DEP-driven microfluidics.
- To address the critical factor of input voltage that influences the portability of microfluidic devices.
Main Methods:
- Review of recent literature on dielectrophoresis (DEP) in microfluidic devices.
- Analysis of strategies to lower the input voltage for DEP applications.
Main Results:
- Advances have been made in reducing the voltage necessary for DEP.
- Lowering input voltage is crucial for enhancing the portability of DEP-based microfluidic devices.
Conclusions:
- Reducing stimulation voltage is key to realizing the full potential of DEP-driven microfluidics for portable diagnostics.
- Further research into low-voltage DEP is essential for developing practical point-of-care devices.
