Nebulization dielectric barrier discharge ionization mass spectrometry: Rapid and sensitive analysis of acenaphthene

A rapid, simple and sensitive method was proposed for low-polar acenaphthene analysis by coupling nebulization with dielectric barrier discharge ionization (N-DBDI). The sample solution was nebulized followed by heating and converted to be gas-phase analyte molecules prior to DBDI. This boosts the collision efficiency of analyte molecules with reactive species and thus the sensitivity, and the high-velocity gas from nebulization guides ions directed to the MS inlet without deflection. The dependence of sensitivity on the operation parameters was systematically investigated. The LOD and LOQ of acenaphthene were determined to be 0.61 ng/L and 2.05 ng/L, respectively, which were superior approximately 30 folds compared to those obtained by other methods. Parameters, including accuracy, precision, reproducibility and utility, were tested to further evaluate the performance of N-DBDI. Real environmental samples, including river water, initial rainwater and mineral water, were analyzed with good accuracy (93.61-103.50%) and satisfactory precision (RSD ≤ 8.92%). These findings suggest that the N-DBDI allows the determination of non/low-polar species at sub-pg/mL possible, and would benefit for the non/low-polar species analysis in real environmental samples.