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β-Cyclodextrin functionalized molybdenum disulfide quantum dots as nanoprobe for sensitive fluorescent detection of
Yinhui Yi1, Wei Zeng2, Gangbing Zhu3
1School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, 212013, PR China; State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University, Changsha, 410082, PR China; Key Laboratory for Analytical Science of Food Safety and Biology, Ministry of Education, PR China.
Abstract:
Through modifying molybdenum disulfide quantum dots (MoS2 QDs) with 3-aminophenyl boronic acid and functionalizing further with hydropropyl-β-cyclodextrin (β-CD), a novel nanoprobe based on β-CD functionalized MoS2 QDs (β-CD-MoS2 QDs) was developed for the fluorescent detection of parathion-methyl (MP). β-CD-MoS2 QDs was characterized with various technologies including transmission electron microscopy, X-ray photoelectron spectroscopy, fluorescence and UV-Vis absorption spectra. As for MP detection, MP was hydrolyzed to p-nitrophenol (p-NP) under the alkaline conditions, and p-NP can enter into the β-CD cavity due to the host-guest recognition capability of β-CD, which then results the fluorescence quenching of nanoprobe. Based on this principle, an enzyme-free fluorescence sensing platform were constructed for MP. Under the optimal conditions, β-CD-MoS2 QDs nanoprobe exhibits wide detection scope (0.01-18.0 ppm) and low detection limits (3.3 ppb) for MP detection. In addition, the nanoprobe has excellent selectivity for MP, and it can be applied to detect MP in real samples.
