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Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis
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Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis

Published on: November 17, 2017

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Nanoparticle-Based Approaches towards the Treatment of Atherosclerosis

Artur Y Prilepskii1, Nikita S Serov1, Daniil V Kladko1

  • 1International Institute "Solution Chemistry of Advanced Materials and Technologies", ITMO University, 191002 Saint Petersburg, Russia.

Pharmaceutics
|November 10, 2020
PubMed

Insights

Nanomedicine offers promising advancements for treating atherosclerosis, an inflammatory disease. Recent research highlights nanocarrier-based drug targeting and theranostic agents for improved plaque management and reduced side effects.

Area of Science:

  • Cardiovascular Research
  • Nanomedicine Applications
  • Inflammatory Disease Therapeutics

Background:

  • Atherosclerosis is a significant, inflammation-associated disease causing widespread morbidity and mortality.
  • Current pharmaceutical interventions for plaque formation and destabilization have limitations and risks.
  • Nanomedicine presents novel strategies for atherosclerosis imaging and treatment.

Purpose of the Study:

  • To review recent advances in nanomedicine for atherosclerosis treatment.
  • To discuss nanocarrier-based drug targeting and theranostic agents.
  • To explore future prospects of nanoformulated therapeutics for inflammatory diseases.

Main Methods:

  • Focused review of scientific literature published since 2015.
  • Emphasis on research from 2019-2020.
  • Analysis of nanocarrier principles, therapeutic approaches, and theranostics.

Main Results:

  • Nanomedicine enables targeted drug delivery, potentially improving atherosclerosis treatment efficacy.
  • Theranostic agents offer combined diagnostic and therapeutic capabilities.
  • Significant progress has been made in nanoformulated therapeutics for inflammatory conditions.

Conclusions:

  • Nanomedicine holds considerable potential for advancing atherosclerosis management.
  • Targeted delivery and theranostics represent key areas of innovation.
  • Further research into nanoformulated therapeutics is crucial for combating atherosclerosis and related inflammatory diseases.

Keywords:
atherosclerosisnanoparticlestarget delivery

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