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Updated: Dec 1, 2025

Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids
Published on: April 25, 2016
Glucocorticoid-induced cardiomyopathy: unexpected conclusion
Taha Sheikh1, Hina Shuja2, Syeda Ramsha Zaidi3
1Department of Internal Medicine, University of Toledo, Toledo, Ohio, USA taha.sheikh@utoledo.edu.
Insights
Glucocorticoid excess, from conditions like Cushing's syndrome, can cause heart failure. This case highlights a rare instance of glucocorticoid-induced dilated cardiomyopathy in a young man with cushingoid features.
Area of Science:
- Cardiology
- Endocrinology
- Internal Medicine
Background:
- Glucocorticoid excess is an under-recognized cause of cardiovascular adverse effects, including hypertension, left ventricular hypertrophy, myocardial infarction, and heart failure.
- While anabolic steroid-induced cardiomyopathy is known, endogenous corticosteroid-induced cardiomyopathy and heart failure are rarely reported.
- Cardiovascular complications are significant sequelae of glucocorticoid excess.
Abstract:
Glucocorticoid excess is an under-recognised cause of cardiovascular adverse effects. The sources can be either endogenous (Cushing's syndrome) or exogenous (Anabolic steroid abuse). Cardiovascular complications due to excess glucocorticoid includes hypertension, left ventricular hypertrophy, myocardial infarction, and heart failure. Although anabolic steroid-induced cardiomyopathy is a well-recognised phenomenon, endogenous corticosteroid-induced cardiomyopathy and heart failure are rarely reported sequelae of glucocorticoid excess in the body. We report a glucocorticoid-induced dilated cardiomyopathy in a 26-year-old African-American man with cushingoid features and symptomatic heart failure.
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