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Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
08:05

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A suspected case of COVID-19 turned into a confirmed case: a case report

Di Yang1, Kai Wei1, Xuesong Gao1

  • 1Beijing Ditan Hospital, Capital Medical University, 8th, Jingshundong Street, Chaoyang District, Beijing, 100015, PR China.

Future Virology
|November 10, 2020
PubMed

Insights

A suspected COVID-19 case was confirmed after four sputum tests. This highlights the importance of repeated nucleic acid testing for accurate SARS-CoV-2 diagnosis in close contacts.

Area of Science:

  • Infectious Diseases
  • Virology
  • Diagnostic Microbiology

Background:

  • COVID-19, caused by SARS-CoV-2, presents with diverse symptoms including respiratory distress.
  • Nucleic acid testing is the gold standard for diagnosing SARS-CoV-2 infection.
  • Chinese diagnostic protocols allow exclusion of COVID-19 after two negative consecutive tests.

Observation:

  • A suspected COVID-19 case with a known close contact history was reported.
  • Initial nucleic acid tests on airway specimens were negative.
  • The patient underwent four sputum sample tests with a minimum 24-hour interval.

Findings:

  • SARS-CoV-2 nucleic acid was eventually detected in sputum samples.
  • The suspected case was confirmed after multiple sputum tests.

Implications:

  • Repeated nucleic acid testing, particularly using sputum, can be crucial for confirming COVID-19 in suspected cases.
  • This case underscores the potential for delayed viral detection.
  • Diagnostic strategies may need to adapt to individual patient presentations and testing modalities.

Keywords:
COVID-19SARS-CoV-2case reportconfirmed casesuspected case

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