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Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
Published on: December 18, 2016
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Olfactory Testing in Temporal Lobe Epilepsy: a Systematic Review.
Brian Y Hwang1, David Mampre2, Rachel Penn3
1Division of Functional Neurosurgery, Department of Neurosurgery, Johns Hopkins School of Medicine, 600 N. Wolfe Street, Meyer 8-181, Baltimore, MD, 21287, USA. bhwang8@jhmi.edu.
Current Neurology and Neuroscience Reports
|November 10, 2020
Summary
Olfactory testing offers a safe, cost-effective bedside tool for temporal lobe epilepsy (TLE) patients. However, standardized testing methods and domains are needed to fully utilize olfactory tests for TLE diagnosis and monitoring.
Area of Science:
- Neurology
- Sensory Science
Background:
- Olfactory testing is a valuable bedside tool for temporal lobe epilepsy (TLE) patients.
- Current methods and relevant olfactory domains for TLE testing lack standardization.
Purpose of the Study:
- To systematically review and evaluate olfactory tests used in TLE.
- To summarize the existing literature on olfactory testing in TLE patients.
Main Methods:
- Systematic literature review.
- Evaluation of various olfactory testing methodologies and their application in TLE.
Main Results:
- Significant variation exists in olfactory test administration, odorants, timing, and grading.
- The Smell Threshold Test and University of Pennsylvania Smell Identification Test are validated for odor detection and identification.
- The Odor Memory/Discrimination Test and Sniffin' Sticks test are validated multi-domain tests.
Conclusions:
- Olfactory testing shows potential for TLE diagnosis, monitoring, and surgical risk assessment.
- Urgent need for rigorous validation, standardization, and comparative analysis of olfactory tests in TLE.
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