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Rosacea and the Microbiome: A Systematic Review.
Hala Daou1, Michela Paradiso2, Kerry Hennessy3
1Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Dermatology and Therapy
|November 10, 2020
Summary
This study explores the gut microbiome
Area of Science:
- Dermatology
- Microbiology
- Gastroenterology
Background:
- Rosacea is a chronic inflammatory skin condition affecting facial skin.
- Its exact cause is unknown, but current research points to the skin's microbiome.
- Emerging evidence suggests a link between gut health and rosacea.
Purpose of the Study:
- To review the literature on the relationship between the gut microbiome and rosacea.
- To explore potential gastrointestinal (GI) pathologies associated with rosacea.
- To summarize current therapeutic strategies for rosacea.
Main Methods:
- A systematic literature review was performed.
- Databases searched include PubMed, Cochrane, and Embase.
- Literature was reviewed up to August 6, 2020.
Main Results:
- The review synthesized findings on the cutaneous microbiome, gut microbiome, and rosacea treatments.
- Associations between rosacea and GI conditions like SIBO, IBS, and IBD were investigated.
- The role of Helicobacter pylori infection was also examined.
Conclusions:
- Further research is needed to clarify the mechanisms connecting GI issues to rosacea.
- The potential of gut-targeted therapies for managing rosacea symptoms requires investigation.

