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Platinum group element-based nanozymes for biomedical applications: an overview
Shao-Bin He1,2, Liu Yang1,2, Meng-Ting Lin1
1Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, School of Pharmacy, Fujian Medical University, Fuzhou, People's Republic of China.
Biomedical Materials (Bristol, England)
|November 10, 2020
Summary
Platinum group element (PGE)-based nanozymes offer enhanced catalytic efficiency and stability for biomedical applications. This review details their synthesis, properties, and potential in biosensing, imaging, and medicine.
Area of Science:
- Nanotechnology
- Materials Science
- Biomedical Engineering
Background:
- Nanozymes, nanomaterials with enzyme-like activities, are rapidly advancing.
- Platinum group element (PGE)-based nanozymes (Pt, Pd, Ru, Rh, Ir, Os) show promise in expanding nanomaterial applications.
Purpose of the Study:
- To review the research progress of PGE-based nanozymes.
- To highlight their synthesis, characterization, and enzyme-like properties.
- To explore their biomedical applications and future perspectives.
Main Methods:
- Review of synthesis and characterization techniques for PGE-based nanozymes.
- Analysis of enzyme-like activities, stability, biocompatibility, and toxicity.
- Evaluation of applications in biosensing, biological medicine, and biomedical imaging.
Main Results:
- PGE-based nanozymes exhibit high catalytic efficiency, large surface area, and stability.
- These properties facilitate applications in biosensing, medical treatments, and imaging.
- Research emphasizes overcoming limitations for enhanced biomedical utility.
Conclusions:
- PGE-based nanozymes represent a significant advancement in nanomaterials for biomedical fields.
- Their unique properties offer solutions for challenges in biological detection and clinical relevance.
- Future research directions focus on optimizing their therapeutic and diagnostic potential.
