Non-Invasive Electrochemical Biosensors Operating in Human Physiological Fluids
Magnus Falk1, Carolin Psotta1,2, Stefan Cirovic1
1Department of Biomedical Science, Faculty of Health and Society, and Biofilms-Research Center for Biointerfaces, Malmö University, 20506 Malmö, Sweden.
Sensors (Basel, Switzerland)
|November 11, 2020
Summary
Non-invasive electrochemical biosensors in bodily fluids like tears and sweat offer convenient healthcare. Addressing current challenges can revolutionize clinical and self-monitoring practices.
Area of Science:
- Biomedical Engineering
- Analytical Chemistry
- Wearable Technology
Background:
- Non-invasive healthcare technologies are crucial for cost-effective and convenient patient monitoring.
- Electrochemical biosensors offer a promising avenue for real-time analysis of physiological fluids.
Purpose of the Study:
- To overview recent advancements in non-invasive electrochemical biosensors.
- To discuss challenges and requirements for biosensors operating in human physiological fluids.
Main Methods:
- Review of electrochemical techniques including amperometry, coulometry, cyclic voltammetry, and impedance spectroscopy.
- Analysis of biosensor performance in secreted human physiological fluids (tears, sweat, saliva, urine).
Main Results:
- Significant progress in developing non-invasive electrochemical biosensors for various bodily fluids.
- Identification of key challenges such as sensor stability, calibration, and multiplexing.
Conclusions:
- Non-invasive biosensing in bodily fluids is complex but holds transformative potential.
- Overcoming current limitations can disrupt traditional clinical diagnostics and personal health monitoring.
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