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Updated: Dec 1, 2025
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Protocols for Vaginal Inoculation and Sample Collection in the Experimental Mouse Model of Candida vaginitis
Published on: December 8, 2011
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Vulvovaginal Candidosis: Current Concepts, Challenges and Perspectives
Valentina Sustr1, Philipp Foessleitner1, Herbert Kiss1
1Department of Obstetrics and Gynecology, Division of Obstetrics and Feto-Maternal Medicine, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.
Journal of Fungi (Basel, Switzerland)
|November 11, 2020
Summary
Vulvovaginal candidosis (VVC), a common yeast infection in women, is often caused by Candida albicans. Understanding its epidemiology, pathogenesis, and diagnosis is key for effective management.
Area of Science:
- Gynecology
- Infectious Diseases
- Mycology
Background:
- Vulvovaginal candidosis (VVC) is a common lower genital tract infection affecting women of reproductive age.
- Candida albicans is the predominant yeast species responsible for VVC, though other non-albicans species can also cause infection.
- Virulence factors of Candida albicans contribute to the development and severity of VVC.
Purpose of the Study:
- To review the current understanding of VVC epidemiology.
- To explore the pathogenesis of VVC, including the role of Candida virulence factors.
- To summarize diagnostic approaches for VVC.
Main Methods:
- This study is a narrative review of existing literature.
- The review synthesizes information on VVC epidemiology, pathogenesis, and diagnosis.
- Current treatment guidelines are referenced but not detailed.
Main Results:
- VVC is a prevalent infection, primarily caused by Candida albicans in immunocompetent women.
- Virulence factors of Candida albicans play a significant role in VVC development.
- Accurate and rapid diagnosis is essential for successful VVC treatment.
Conclusions:
- A comprehensive understanding of VVC's epidemiology, pathogenesis, and diagnostic methods is presented.
- Early and reliable diagnosis is critical for effective management of VVC.
- Clinical management of VVC should adhere to established treatment guidelines.
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