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Metastasis

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

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Related Experiment Video

Updated: Dec 1, 2025

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

Recent Scientific Developments in Metastatic Prostate Cancer.

Isabel Heidegger¹

¹Department of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.

|November 11, 2020

Summary

Advanced prostate cancer treatments have evolved significantly. New therapies offer improved outcomes for patients with metastatic disease.

Keywords:

biomarker metastatic castration-resistant prostate cancer metastatic hormone-sensitive prostate cancer personalized therapy

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Last Updated: Dec 1, 2025

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

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Published on: March 6, 2018

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Published on: August 29, 2016

Intra-Cardiac Injection of Human Prostate Cancer Cells to Create a Bone Metastasis Xenograft Mouse Model

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Published on: November 4, 2022

Area of Science:

Oncology
Medical Science

Background:

The management of advanced prostate cancer has undergone substantial transformation.
Recent therapeutic advancements have reshaped treatment paradigms.

Discussion:

Novel therapeutic strategies are emerging for advanced prostate cancer.
Understanding these changes is crucial for effective patient care.

Key Insights:

The treatment landscape for advanced prostate cancer is rapidly evolving.
New therapeutic options are improving patient prognoses.

Outlook:

Continued research is expected to yield further treatment innovations.
Future directions in advanced prostate cancer therapy hold promise.