Thyroid Lobectomy for Low to Intermediate Risk Differentiated Thyroid Cancer.

Area of Science:

• Endocrinology
• Surgical Oncology
• Oncology

Background:

• Differentiated thyroid cancer (DTC) accounts for the majority of thyroid malignancies.
• Recent trends advocate for less aggressive treatment strategies in low to intermediate-risk DTC.
• Thyroid lobectomy is emerging as a conservative surgical option.

Purpose of the Study:

• To evaluate the advantages and disadvantages of thyroid lobectomy for low to intermediate-risk DTC.
• To define criteria for patient selection for thyroid lobectomy.
• To analyze the oncological outcomes associated with thyroid lobectomy.

Main Methods:

• Review of recent publications and guidelines on DTC treatment.
• Analysis of studies comparing thyroid lobectomy to more extensive surgical procedures.
• Examination of criteria for patient selection based on tumor characteristics.

Main Results:

• Thyroid lobectomy can decrease short- and long-term postoperative morbidity.
• This approach maintains an excellent prognosis for carefully selected DTC patients.
• Specific macroscopic and microscopic criteria are crucial for successful patient selection.

Conclusions:

• Thyroid lobectomy is a viable and safe option for select low to intermediate-risk DTC.
• Careful patient selection based on defined criteria is paramount for optimal outcomes.
• This approach aligns with the "more is less" strategy in DTC management.