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A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
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Continuous renal replacement therapy in critically ill children: single-center experience
Gül Hatice Erkol Tuncer1, Mesiha Ekim1,2, Emel Okulu1,3
1Department of Pediatrics, Faculty of Medicine, Ankara University, Ankara, Turkey
Turkish Journal of Medical Sciences
|November 11, 2020
Summary
Continuous renal replacement therapy (CRRT) is a vital treatment for critically ill children. This study found CRRT improved outcomes, especially in newborns, highlighting its life-saving potential in pediatric intensive care.
Area of Science:
- Pediatric Nephrology
- Critical Care Medicine
- Neonatology
Background:
- Continuous renal replacement therapy (CRRT) offers significant benefits for critically ill children.
- Understanding CRRT's application in pediatric and neonatal intensive care units is crucial for optimizing interventions.
Purpose of the Study:
- To describe CRRT indications, methods, demographics, and outcomes in a pediatric intensive care unit.
- To identify areas for improvement in unit-based CRRT interventions based on patient data.
Main Methods:
- Retrospective evaluation of medical charts for patients receiving CRRT.
- Study period: February 2010 to November 2015 at a single center.
Main Results:
- Fifty patients were included; 28% were newborns. Common indications included acute kidney injury (40%) and fluid overload (30%).
- Continuous venovenous hemodiafiltration (CVVHDF) was the most frequent method (72%). Overall survival was 42%, with significantly higher survival in newborns (P = 0.046).
Conclusions:
- CRRT is a life-saving therapy for critically ill children with acute kidney injury and fluid overload.
- Experienced teams can successfully apply CRRT across all pediatric ages and weights.
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