Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The sunburn cell.

A R Young1

  • 1Department of Photobiology, United Medical School of Guy's Hospital, University of London, UK.

Photo-Dermatology
|June 1, 1987
PubMed
Summary
This summary is machine-generated.

Sunburn cells, a result of UV radiation damage to skin cells, undergo premature keratinization. Their ultimate fate, likely apoptosis, remains under investigation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cerium doped yttrium aluminum perovskite scintillator as an absolute ultracold neutron detector.

The Review of scientific instruments·2024
Same author

Scintillation characteristics of the EJ-299-02H scintillator.

The Review of scientific instruments·2024
Same author

First Observation of Cyclotron Radiation from MeV-Scale e^{±} following Nuclear β Decay.

Physical review letters·2023
Same author

The effects of exposure to solar radiation on human health.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology·2023
Same author

Environmental effects of stratospheric ozone depletion, UV radiation, and interactions with climate change: UNEP Environmental Effects Assessment Panel, Update 2021.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology·2022
Same author

Neutron interferometer crystallographic imperfections and gravitationally induced quantum interference measurements.

Physical review. A·2022
Same journal

Phototherapy for neonatal hyperbilirubinemia.

Photo-dermatology·1989
Same journal

Solar purpura is not related to polymorphous light eruption.

Photo-dermatology·1989
Same journal

Cis-urocanic acid stereospecifically modulates human monocyte IL-1 production and surface HLA-DR antigen expression, T-cell IL-2 production and CD4/CD8 ratio.

Photo-dermatology·1989
Same journal

Local increase in interleukin-1-like activity following UVB irradiation of human skin in vivo.

Photo-dermatology·1989
Same journal

Photocarcinogenesis is retarded by a partly photodegraded solution of para-aminobenzoic acid.

Photo-dermatology·1989
Same journal

Effect of ultraviolet B on nonimmunologic contact reactions induced by dimethyl sulphoxide, phenol and sodium lauryl sulphate.

Photo-dermatology·1989
See all related articles

Area of Science:

  • Dermatology
  • Photobiology
  • Cell Biology

Background:

  • Sunburn cells are a hallmark of mammalian epidermis following UV radiation exposure.
  • DNA damage is implicated as a key factor in sunburn cell formation.
  • The precise mechanisms driving sunburn cell development are not fully understood.

Purpose of the Study:

  • To investigate the characteristics and potential fate of sunburn cells.
  • To explore the role of DNA damage in sunburn cell formation.
  • To understand the process of abnormal keratinization in sunburn cells.

Main Methods:

  • Histological examination of mammalian epidermis after UV exposure.
  • Analysis of cellular changes, including nuclear and cytoplasmic morphology.

Related Experiment Videos

  • Inference of cellular processes based on observed characteristics.

    • Main Results:

    • Sunburn cells exhibit a pyknotic nucleus and eosinophilic cytoplasm.
    • UVB, UVC, and UVA (with psoralens) induce sunburn cell formation.
    • Sunburn cells represent keratinocytes undergoing abnormal, premature keratinization.

    Conclusions:

    • Sunburn cells are a distinct cellular response to UV-induced DNA damage.
    • The ultimate fate of sunburn cells may involve desquamation or phagocytosis.
    • Sunburn cells can be considered a form of apoptosis, or programmed cell death.