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Clozapine-Induced Pneumonitis: A Case Report
Tyler Torrico1, Ronald O Crandall2, Carlos Meza1
1Department of Psychiatry, Kern Medical, Bakersfield, CA, United States.
Frontiers in Psychiatry
|November 11, 2020
Summary
Clozapine can cause rare drug-induced pneumonitis, mimicking sepsis. Early recognition is crucial to avoid misdiagnosis and unnecessary antibiotic treatment in patients with schizophrenia or schizoaffective disorder.
Area of Science:
- Psychiatry
- Pulmonology
- Pharmacology
Background:
- Clozapine is a vital antipsychotic for treatment-resistant schizophrenia and suicidal behavior.
- Its use is limited by adverse reactions, notably neutropenia and infection risk.
- Rare cases of non-neutropenic, non-infectious drug-induced lung disease (pneumonitis) exist.
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