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Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model
05:32

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model

Published on: August 11, 2023

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COVID-19 and stroke, a case series and review of literature

Hisham Elkhider1, Faisal Ibrahim2, Rohan Sharma1

  • 1Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

Brain, Behavior, & Immunity - Health
|November 11, 2020
PubMed

Insights

Severe COVID-19 can cause acute ischemic strokes (AIS) in patients under 60. This study examined four such cases, highlighting common clinical and laboratory findings associated with this serious complication.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Cardiology

Background:

  • Coronavirus Disease 2019 (COVID-19) is a global pandemic with increasing cases.
  • Multisystem involvement, including the central nervous system (CNS) and peripheral nervous system (PNS), is reported in COVID-19.
  • Acute ischemic strokes (AIS) are an emerging complication of COVID-19.

Purpose of the Study:

  • To analyze the characteristics, clinical outcomes, and laboratory and imaging results of patients with COVID-19 and AIS.
  • To identify common features among patients experiencing AIS as a complication of severe COVID-19.

Main Methods:

  • Retrospective analysis of four patients diagnosed with both COVID-19 and AIS.
  • Review of patient demographics, clinical presentation, laboratory markers (e.g., D-dimer, inflammatory markers), and neuroimaging findings.

Main Results:

  • All four patients were younger than 60 years old.
  • Patients presented with hypoxemic respiratory failure due to pneumonia.
  • Elevated D-dimer and inflammatory markers were consistently observed in the studied patients.

Conclusions:

  • Acute ischemic strokes are a recognized complication in individuals with severe COVID-19.
  • The findings suggest a potential link between severe COVID-19, hypoxemic respiratory failure, and AIS in younger adults.
Abstract

Keywords:
Covid-19Stroke

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